Department of Experimental and Clinical Neuropathology MMRI
Clinical, anatomical and histological diagnosis
Histological diagnosis: Meningoencephalitis lymphocytaria. Haemorrhagia subarrachnoidealis reecens. Autopsy examination of 44-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained by Hematoxylin-eosin, Holzer and Heidenhain’s azan. Additionally, frozen section was stained by Cresyl violet.There was significant edema and congestion throughout the CUN. All vessels were filled with blood, and exudative fluid, Virchow–Robin spaces were widened and vascular-tissue junction relaxed. In the adventitia of individual vessels, mainly in the centrum semiovale, inflammatory infiltrates consisted mostly of lymphocytes were observed. Prominent glial activation and proliferation were noticed. Homogenization in some cortical nerve cells was seen. In the subarachnoid space in the left hemisphere in the fissures of the lateral occipitotemporal and middle temporal ganglia, fresh blood was seen. Besides that, in the soft meninges, slight infiltrates of lymphocytic cells near vessels or in the connective tissue. A lymphocytic infiltration visible also on a limited area in the fissure between the occipital lobes on the left side..
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Mossakowski Medical Research Institute PAS
Library of the Mossakowski Medical Research Institute PAS
Feb 1, 2022
Jun 23, 2021
41
https://rcin.org.pl./publication/229471
Edition name | Date |
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opis nr 213/66 | Feb 1, 2022 |
Mossakowski, Mirosław Jan (1929–2001)
Mossakowski, Mirosław Jan (1929–2001)
Mossakowski, Mirosław Jan (1929–2001)