Institutional creator:

Department of Experimental and Clinical Neuropathology MMRI

Contributor:

M.Marciniak, dr

Description:

Clinical, anatomical and histological diagnosis

Abstract:

Histological diagnosis: Laesiones cellularae disperae. Autopsy examination of 11-week-old infant was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained by Hematoxylin-eosin, Cresyl violet and Van Gieson's stain.Due to the extensive putrefactive process, the specimen were difficult to evaluate. Throughout the central nervous system, features of tissue swelling were found, with disruption of interlobular oligodendroglial, thinning of perivascular spaces and slight thickening of the glia around some vessels. Despite the significant putrefaction process, there were areas with preserved nerve cells, which revealed features of a chronic disease process. In the cerebellum, a complete separation of the molecular layer from the granular cell layer was seen. The remaining Purkinje cells were often ischemically altered or disintegrated.

Format:

pdf

Resource Identifier:

oai:rcin.org.pl:193418

Language:

pol

Language of abstract:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open