Twórca instytucjonalny:

Department of Experimental and Clinical Neuropathology MMRI

Współtwórca:

M.Marciniak, dr ; K. Wiśniewska, dr

Opis:

Clinical, anatomical and histological diagnosis

Abstrakt:

Histological diagnosis: Encephalomacia multiplices hemisphaerii dextri et trunci cerebri. Autopsy examination of 62-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained with Hematoxylin-eosin, van Gieson and PAS method.The right parietal lobe showed a focus of malacia destroying the cortex and white matter. This focus was in the stage of advanced glial-mesodermal organization. In the center of the focus, significant loss of neural tissue and connective tissue network with macrophages were seen. Vessels with symptomatic infiltrates and perivascular necrosis were seen in places. Significant nerve cell loss, chronic ischemic disorder and fatty degeneration of neurons were observed in the cortex. Small foci of subcortical and cortical malacia were also observed, also at the glial-mesodermal organization stage. In the right occipital lobe, an old focus of softening with a centrally located cavity was seen. There was a very large connective tissue reaction in some areas. Very large atherosclerotic lesions were seen in vessels throughout the central nervous system. The largest focus of malacia was located above the olive.

Format:

pdf

Identyfikator zasobu:

oai:rcin.org.pl:193395

Język:

pol

Język streszczenia:

eng

Prawa:

Creative Commons Attribution BY 4.0 license

Zasady wykorzystania:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitalizacja:

Mossakowski Medical Research Institute PAS

Lokalizacja oryginału:

Library of the Mossakowski Medical Research Institute PAS

Dofinansowane ze środków:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Dostęp:

Open