Institutional creator:

Department of Experimental and Clinical Neuropathology MMRI

Contributor:

H. Lewicka-Wysocka, dr

Description:

Clinical, anatomical and histological diagnosis

Abstract:

Histological Diagnosis: Encephalomacia hemisphaerii dextri in regione lobus temporalis et nucleorum basalium. Autopsy examination of 75-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained with hematoxylin-eosin, PAS and Van Gieson's method.An extensive focus of encephalomalacia was present in the right hemisphere, partially destroying the lateral thalamic nucleus, internal capsule, white matter of the temporal lobe, and cortex of the hippocampus and lateral occipitotemporal valve. The focus was in a stage of advanced dissection. Dissolving tissue and numerous macrophages were visible in the center. There was white matter swelling around the foci, stimulation of astroglia, and all vessels filled with blood. A symptomatic reaction was seen around some vessels. The cortex around the foci had multiple neuronal atrophy, ischemic, chronic type disease and cellular steatosis. There were features of congestion throughout the CNS and in the meninges. The Virchov-Robin spaces were dilated, the tissue-vascular borderline relaxed. In the meninges macrophages and histiocyte-like cells were observed around the vessels. Pseudocalcium deposits were seen in the choroid plexus

Format:

pdf

Resource Identifier:

oai:rcin.org.pl:193357

Language:

pol

Language of abstract:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open