Institutional creator:

Department of Experimental and Clinical Neuropathology MMRI

Contributor:

H.Lewicka-Wysocka, lek.

Place of publishing:

Warsaw

Description:

Clinical, anatomical and histological diagnosis

Abstract:

Histological diagnosis: Encephalomalacia status lacunaris. Arterosclerosis cerebri. Autopsy examination of 77-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained with with Hematoxylin-eosin and Van Gieson's method.The specimen taken from the focus showed necrotic tissue with reduced number of cellular elements, containing numerous circular hemorrhages. The cortex showed diffuse cellular desolation and locally incomplete necrosis. The cerebellum showed thinning of the granular layer. Severely advanced vascular atherosclerosis and obliteration of the layered structure of vascular walls, fragmentation and disintegration of the internal elastic membrane were observed. Small caliber vessels were often vitrified with overgrowth of the lumen. Several larger lacunae were visible in the basal ganglia at medium-sized vessels and extensive spongiosis with thinning of the tissue at capillaries.

Format:

pdf

Resource Identifier:

oai:rcin.org.pl:197154

Language:

pol

Language of abstract:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open