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File of histopathological evaluation of nervous system diseases (1965) - nr 107/65
Institutional creator:Department of Experimental and Clinical Neuropathology MMRI
Contributor: Place of publishing: Date issued/created: Description:Clinical, anatomical and histological diagnosis
Subject and Keywords:Vasular diseases - encephalomacia. Status lacunaris
Abstract:Histological diagnosis: Encephalomalacia status lacunaris. Arterosclerosis cerebri. Autopsy examination of 77-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained with with Hematoxylin-eosin and Van Gieson's method.The specimen taken from the focus showed necrotic tissue with reduced number of cellular elements, containing numerous circular hemorrhages. The cortex showed diffuse cellular desolation and locally incomplete necrosis. The cerebellum showed thinning of the granular layer. Severely advanced vascular atherosclerosis and obliteration of the layered structure of vascular walls, fragmentation and disintegration of the internal elastic membrane were observed. Small caliber vessels were often vitrified with overgrowth of the lumen. Several larger lacunae were visible in the basal ganglia at medium-sized vessels and extensive spongiosis with thinning of the tissue at capillaries.
Resource type: Format: Language: Language of abstract: Rights:Creative Commons Attribution BY 4.0 license
Terms of use:Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -
Digitizing institution:Mossakowski Medical Research Institute PAS
Original in:Library of the Mossakowski Medical Research Institute PAS
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