Institutional creator:

Department of Experimental and Clinical Neuropathology MMRI

Contributor:

L.Iwanowski, dr

Place of publishing:

Warsaw

Description:

Clinical, anatomical and histological diagnosis

Abstract:

Histological diagnosis: Arterio et arteriosclerosis gradus mediocris. Atrophia simplex. Status lacunaris. Autopsy examination of 78-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained with Hematoxylin-eosin, Heidenhain and Van Gieson's method.In analyzed specimens, significant thinning of neural cellular elements was observed in both cortex and brain stem, as well as strongly expressed features of ischemia in a significant proportion of cells. Generalized gliosis was visible. In the cerebral cortex, regional necrosis was seen. In the white matter of the cerebral hemispheres, sinuses of various sizes surrounded by starchy bodies were locally found; in the midbrain, partial disintegration of substancia nigra cells was seen; within the cerebellum, partial loss of Purkinje cells was observed. Medium-caliber vessels had thin smooth muscle layer and thick adventitia. Staining for myelin was less intense in areas of thinned tissue.

Format:

pdf

Resource Identifier:

oai:rcin.org.pl:197024

Language:

pol

Language of abstract:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open