Twórca instytucjonalny:

Department of Experimental and Clinical Neuropathology MMRI

Współtwórca:

A. Taraszewska, dr

Miejsce wydania:

Warsaw

Opis:

Clinical, anatomical and histological diagnosis

Abstrakt:

Histological diagnosis: Encephalomalacia recens in regione nucleorum basalium. Encephalomalacia inveterata cerebelli. Oedema cerebri. Ar teriosclerosis gradu mediocri. Embolia arteriae cerebri med.Autopsy examination of 47-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained with Cresyl-violet and Van Gieson's method.The left basal ganglia revealed an early stage of encephalomalacia. Extensive cell atrophy and prominent ischemic changes in the remaining cells were seen. Features of edema, loosening of tissue structure and widening of perivascular spaces were observed. Leukocyte infiltrates were present around the vessels, vascular endothelium was swollen, and hemorrhages were found locally. The glia was stimulated. In the cerebellum, a foci of malacia in the stage of advanced dissection and glial-mesodermal organization was observed, with numerous macrophages and a large connective tissue reaction. In the vicinity, the tissue structure was severely thinned, atrophy of the Purkinje cell layer and granular layer was evident. the Bergman glia was proliferating, the Purkinje cells showed features of chronic disease. The cerebral vessels were fibrously altered. There were blood masses separated by connective tissue elements in the lumen of the middle cerebral artery.

Format:

pdf

Identyfikator zasobu:

oai:rcin.org.pl:197046

Język:

pol

Język streszczenia:

eng

Prawa:

Creative Commons Attribution BY 4.0 license

Zasady wykorzystania:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitalizacja:

Mossakowski Medical Research Institute PAS

Lokalizacja oryginału:

Library of the Mossakowski Medical Research Institute PAS

Dofinansowane ze środków:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Dostęp:

Open