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Department of Experimental and Clinical Neuropathology MMRI
Clinical, anatomical and histological diagnosis
Histological diagnosis: Encephalitis lymphocytaria probabiliter parainfectiosa.Autopsy examination of 5-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain frozen sections stained with Hematoxylin-eosin and cresyl-violet method. There was diffuse glial thickening in the white matter of the hemispheres and in the basal ganglia. In the white matter of the frontal and central gyri, in the basal ganglia, and in the occipital region, massive perivascular lymphocytic infiltrates were seen. The gray matter was rather spared. The architecture of cortex and ganglia was normal. Large vascular congestion and stasis were observed in the cerebellum. There were no inflammatory changes in the brainstem, but discrete lymphocytic infiltrates in the meninges. The picture was consistent with acute inflammatory reactions of the central nervous system, without characteristic features, seen in the course of various general infections, mostly of viral nature.
Creative Commons Attribution BY 4.0 license
Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -
Mossakowski Medical Research Institute PAS
Library of the Mossakowski Medical Research Institute PAS
Feb 1, 2022
Oct 1, 2021
34
https://rcin.org.pl./publication/251025
Edition name | Date |
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opis nr 24/62 | Feb 1, 2022 |