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Department of Experimental and Clinical Neuropathology MMRI
Clinical, anatomical and histological diagnosis
Histological diagnosis: Encephalitis gripposa.Autopsy examination of 3-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained with Hematoxylin-eosin.Small inflammatory infiltrates near vessels were restricted to a few to a dozen lymphocyte-like elements. The infiltrates near veins were slightly more abundant, usually concentrated in one part of the vessel. In the walls of even very small arteries, vitreous lesions were present. Thrombi were formed in the arterioles. Loose lymphocytic infiltrates were found in the meninges. Altered vessels were observed more in the hemispheres, in the white matter, as compared to the stem and cerebellum. Besides, there were features of generalized edema and generalized neuronal ischemic changes throughout the brain. However, in the context of decaying features of the entire specimen, the evaluation of these types of lesions was difficult. The brain picture in combination with the clinical picture may correspond to the so-called influenza inflammation, or para-infectious inflammation.
Creative Commons Attribution BY 4.0 license
Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -
Mossakowski Medical Research Institute PAS
Library of the Mossakowski Medical Research Institute PAS
Oct 11, 2022
Aug 20, 2021
28
https://rcin.org.pl./publication/241478
Edition name | Date |
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opis nr 169/64 | Oct 11, 2022 |