Institutional creator:

Department of Experimental and Clinical Neuropathology MMRI

Contributor:

E.Osetowska, dr hab.

Place of publishing:

Warsaw

Description:

Clinical, anatomical and histological diagnosis

Abstract:

Histological diagnosis:Ecncephalitis lymphocytaria acuta.Autopsy examination of 14-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain frozen sections stained with Hematoxylin-eosin.The predominant feature of the case was acute perivascular and pericellular edema in both white and grey matter. Perivascular transudates were seen in the white matter. A distinct edematous "halo" was observed around oligodendrocytes and astrocytes, causing fiber tracts in the white matter to be dispersed. In the cortex, especially the parietal region, spongy thinning of the structure was seen in several places. Medium and small vessels were filled with blood. Around the medium-sized vessels, sparse lymphocytic infiltrates consisting of several to dozens of elements were visible in the walls. The structure of the cerebral cortex and grey nuclei was preserved - individual cells were obliterated with tigrolysis. The meninges showed venous stasis, slight lymphocytic and mesothelial infiltrates. The picture corresponds to very acute, "fulminant" lymphocytic encephalitis, occurring spontaneously or accompanying infectious diseases (most often in the course of influenza epidemics).

Format:

pdf

Resource Identifier:

oai:rcin.org.pl:213878

Language:

pol

Language of abstract:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open