Institutional creator:

Department of Experimental and Clinical Neuropathology MMRI

Contributor:

Wiśniewska, K. dr

Place of publishing:

Warsaw

Description:

Clinical, anatomical and histological diagnosis

Abstract:

Histological diagnosis: Atrophia cerebri. Arteriosclerosis cerebri.Autopsy examination of 71-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained with Hematoxylin-eosin and van Gieson method and frozen section s stain with Bielschowsky method.In the cortex, cellular desolations were observed, obliterating in parts its layered structure. Nerve cells were often steatotic, some showed features of chronic disease. The changes were most pronounced in the third and fifth layer and perivascularly. Large atherosclerotic lesions were present. The vessels, especially in the basal ganglia and white matter, presented changes typical of vitrification and fibrosis, fibrous changes were observed in the cortex. Lymphocyte-like cells, macrophages with hemosiderin and pseudocalcium salts were seen near some vessels. Besides, there were features of congestion and edema. In the meninges, single macrophages were present in some areas. No senile plaques were found in the cortex or basal ganglia.

Format:

pdf

Resource Identifier:

oai:rcin.org.pl:210133

Language:

pol

Language of abstract:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open