Institutional creator:

Department of Experimental and Clinical Neuropathology MMRI

Contributor:

Wiśniewska, K. dr

Place of publishing:

Warsaw

Description:

Clinical, anatomical and histological diagnosis

Abstract:

Histological diagnosis: Encephalomalacia cerebri. Arteriosclerosis cerebri.Autopsy examination of 77-year-old patient was performed. Neuropathological evaluation in light microscopy was based on brain paraffin sections stained with Hematoxylin-eosin and van Gieson method.A focus of diffuse necrosis was seen in the frontal lobe, destroying the white matter and cortex over a large area, preserving the fine layer almost completely. The focus was covered with macrophages, with little vascular reaction, causing complete tissue disintegration in places, and a spongy state in places. The cortex showed extensive neuronal atrophy and obliterated layered pattern. The activation and proliferation of the glia was evident, especially in the vicinity of the focus. Small macrophage infiltrates were evident in the meninges; vessels were hypertrophic with fibrous changes.

Format:

pdf

Resource Identifier:

oai:rcin.org.pl:206071

Language:

pol

Language of abstract:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open