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Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular
Muscle segment examination in light & electron microscopy
A 65-year-old patient with suspected myopathy was examined. A biceps biopsy was performed.Muscle fibers of a diameter within a normal range, with preserved myofibril architecture, characterized by the presence of numerous small vacuoles, probably derived from the sarcoplasmic reticulumwere seen.Fibers characterized by the accumulation of a huge amount of autophagal structures and fat dropletswere observed. In some of these fibres , abnormal myofibrils lacking the A line was seen, in somethe entire muscle fiber was filled by autophagal and fat structures.Microscopic image of the biopsy may suggest adipose triglyceride lipase (ATGL) deficiency leading to neutral lipid storage disease.
Creative Commons Attribution BY 4.0 license
Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -
Mossakowski Medical Research Institute PAS
Library of the Mossakowski Medical Research Institute PAS
Mar 23, 2022
Jun 25, 2020
83
https://rcin.org.pl./publication/161707
Edition name | Date |
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opis nr 1-2/13 | Mar 23, 2022 |