Title:

Files for neuromuscular diseases (2013) - nr 1-2/13

Creator:

Fidziańska-Dolot, Anna (1930–2015)

Contributor:

Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular

Place of publishing:

Warsaw

Date issued/created:

2013

Description:

Muscle segment examination in light & electron microscopy

Subject and Keywords:

Miopathy

Abstract:

A 65-year-old patient with suspected myopathy was examined. A biceps biopsy was performed.Muscle fibers of a diameter within a normal range, with preserved myofibril architecture, characterized by the presence of numerous small vacuoles, probably derived from the sarcoplasmic reticulumwere seen.Fibers characterized by the accumulation of a huge amount of autophagal structures and fat dropletswere observed. In some of these fibres , abnormal myofibrils lacking the A line was seen, in somethe entire muscle fiber was filled by autophagal and fat structures.Microscopic image of the biopsy may suggest adipose triglyceride lipase (ATGL) deficiency leading to neutral lipid storage disease.

Resource type:

Text

Detailed Resource Type:

Photography ; Files

Format:

pdf

Language:

pol

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open