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Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular
Muscle segment examination in light & electron microscopy
An 26-year-old patient with suspected myopathy was examined. A biopsy of quadriceps sinisterwas performed. Ultrastructural assessment showed morphological changes within muscle fibers andglycogen storage under sarcolemma and in the interfibrillary space (Figs. 1-7). Glycogen was alsopresent in mitochondria (Fig. 8).Analysis of muscle fibers in PAS and PAS staining diastase showed the accumulation of PASpositive substance corresponding to glycogen. Muscle phosphorylase activity is significantlyreduced. These data allow the diagnosis of type V glycogenosis.
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Mossakowski Medical Research Institute PAS
Library of the Mossakowski Medical Research Institute PAS
Feb 1, 2022
Feb 18, 2020
53
https://rcin.org.pl./publication/111758
Edition name | Date |
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opis nr 12/13 | Feb 1, 2022 |
Fidziańska-Dolot, Anna (1930–2015)