Twórca instytucjonalny:

Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular Diseases

Współtwórca:

Walczak, Ewa

Miejsce wydania:

Warsaw

Opis:

Electron microscopy analysis of the heart biopsy

Abstrakt:

Dilated cardiomyopathy. Ultrastructural analysis revealed a number of abnormalities in the cardiomyocytes structure.Changed sarcomere pattern, disorganization of myofibrils and in many areas their complete atrophy were observed. Mitochondria partially devoid of mitochondrial cristae were seen in the sarcoplasm and connective tissue was abundant in the extracellular space. Cardiomyocyte nuclei were abnormally shaped, nuclear envelope was corrugated ,with numerous indentations, and in some nucler broken.Mitochondria were characterized by bright matrix and partial loss of cristae . Mitochondria with a dark mitochondrial matrix, containing characteristic inclusions or glycogen in their interior, as well as giant mitochondria, many times larger than normal, were also observed .

Szczegółowy typ zasobu:

Files ; Photography

Format:

pdf

Identyfikator zasobu:

oai:rcin.org.pl:162256

Język:

pol ; eng

Prawa:

Creative Commons Attribution BY 4.0 license

Zasady wykorzystania:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitalizacja:

Mossakowski Medical Research Institute PAS

Lokalizacja oryginału:

Library of the Mossakowski Medical Research Institute PAS

Dofinansowane ze środków:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Dostęp:

Open