Institutional creator:

Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular Diseases

Contributor:

Walczak, Ewa ; Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular Diseases

Place of publishing:

Warsaw

Description:

Electron microscopy analysis of the heart biopsy

Abstract:

Ultrastructural analysis revealed changes in sarcomere pattern, myofibrils disruption and disorganization. Features characteristic for laminopathy were observed. The nuclei of cardiomyocytes were abnormally shaped, the nuclear envelope was corrugated, with numerous indentations. Focally breaks in the nuclear membrane were seen . Many nuclei contained cellular organelles or membrane-surrounded structures inside .Lipofuscin deposits and myelin-like bodies were observed in some areas.

Detailed Resource Type:

Files ; Photography

Format:

pdf

Resource Identifier:

oai:rcin.org.pl:159325

Language:

pol ; eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open