Subtitle:

Neoplastic cell transformation by viruses

Publisher:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Abstract:

Tumor-inducing viruses occur in several taxonomic groups. All RNA tumorviruses belong to retrovirus family, but the DNA tumor viruses come from several different groups. Their oncogenic potential is associated with their replication strategy, and in a vast majority of cases oncogenic transformation occursonly ifthe viral life cycle is aborted. The oncogenic phenotype results from discrete changes in the expression of key cellular control genes: oncogenes and tumor suppressor genes. Most often, the retroviruses cause the activation ofoncogenes, and DNA tumor viruses usually target tumor suppressor genes.

Relation:

Biotechnologia, vol.56, 1 (2002)-.

Volume:

56

Issue:

1

Start page:

87

End page:

104

Detailed Resource Type:

Article

Format:

application/pdf

Resource Identifier:

0860-7796 ; oai:rcin.org.pl:138391 ; IChB B-52

Source:

Library of Institute of Bioorganic Chemistry PAS

Language:

pol

Language of abstract:

eng

Temporal coverage:

1988-2010

Rights:

Creative Commons Attribution BY-SA 4.0 license

Terms of use:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitizing institution:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Original in:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open