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Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular
Muscle segment examination in light & electron microscopy
A 1-month old patient with suspected neuro-muscular disease was examined. A biopsy ofquadriceps sinister was performed.Electronmicroscopy analysis revealed no significant ultrastructural changes in some muscle fibers.They were characterized by normal myofibrils and sub-membranous located cell nuclei. Withinsome mitochondria, damage of mitochondrial cristae was observed.Single fibers ofsmall diameter and centrally located nuclei, what suggest their incomplete maturitywere visible. Widening of the sarcoplasmic grid was seen.In some fibres, the phenomenon of external and internal fission of the nuclear membrane andformation of “vacuoles” was observed.
Creative Commons Attribution BY 4.0 license
Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -
Mossakowski Medical Research Institute PAS
Library of the Mossakowski Medical Research Institute PAS
Feb 1, 2022
Jun 22, 2020
34
https://rcin.org.pl./publication/111845
Edition name | Date |
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opis nr 43/13 | Feb 1, 2022 |