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Files for neuromuscular diseases (2013) - nr 43/13
Creator:Fidziańska-Dolot, Anna (1930–2015)
Contributor:Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular
Place of publishing: Date issued/created: Description:Muscle segment examination in light & electron microscopy
Abstract:A 1-month old patient with suspected neuro-muscular disease was examined. A biopsy ofquadriceps sinister was performed.Electronmicroscopy analysis revealed no significant ultrastructural changes in some muscle fibers.They were characterized by normal myofibrils and sub-membranous located cell nuclei. Withinsome mitochondria, damage of mitochondrial cristae was observed.Single fibers ofsmall diameter and centrally located nuclei, what suggest their incomplete maturitywere visible. Widening of the sarcoplasmic grid was seen.In some fibres, the phenomenon of external and internal fission of the nuclear membrane andformation of “vacuoles” was observed.
Resource type: Detailed Resource Type: Format: Language: Rights:Creative Commons Attribution BY 4.0 license
Terms of use:Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -
Digitizing institution:Mossakowski Medical Research Institute PAS
Original in:Library of the Mossakowski Medical Research Institute PAS
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