Twórca instytucjonalny:

Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular Diseases

Współtwórca:

Walczak, Ewa

Miejsce wydania:

Warsaw

Opis:

Electron microscopy analysis of the heart biopsy

Abstrakt:

Ultrastructural analysis revealed myofibrilar disruption and disorganization,focally significant or complete loss of myofibrils,resulting in the formation of vacuolated spaces, also under the sarcolemma and in the vicinity of nuclei (Figs.1-12).Features characteristic for laminopathy were observed. The nuclei of cardiomyocytes were abnormally shaped,the nuclear envelope was corrugated,with numerous indentations (Figs. 13-17). Altered mitochondria,characterized by bright mitochondrial matrix,loss or abnormal arrangement of cristae were present.Autophagy was locally observed (Figs.18-20).

Szczegółowy typ zasobu:

Files ; Photography

Format:

pdf

Identyfikator zasobu:

oai:rcin.org.pl:162245

Język:

pol ; eng

Prawa:

Creative Commons Attribution BY 4.0 license

Zasady wykorzystania:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitalizacja:

Mossakowski Medical Research Institute PAS

Lokalizacja oryginału:

Library of the Mossakowski Medical Research Institute PAS

Dofinansowane ze środków:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Dostęp:

Open