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Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular Diseases
Electron microscopy analysis of the heart biopsy
Ultrastructural analysis revealed myofibrilar disruption and disorganization,focally significant or complete loss of myofibrils,resulting in the formation of vacuolated spaces, also under the sarcolemma and in the vicinity of nuclei (Figs.1-12).Features characteristic for laminopathy were observed. The nuclei of cardiomyocytes were abnormally shaped,the nuclear envelope was corrugated,with numerous indentations (Figs. 13-17). Altered mitochondria,characterized by bright mitochondrial matrix,loss or abnormal arrangement of cristae were present.Autophagy was locally observed (Figs.18-20).
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Mossakowski Medical Research Institute PAS
Library of the Mossakowski Medical Research Institute PAS
Feb 1, 2022
Feb 17, 2021
34
https://rcin.org.pl./publication/196054
Edition name | Date |
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laminopatia - 55/10 | Feb 1, 2022 |
Fidziańska-Dolot, Anna (1930–2015)
Fidziańska-Dolot, Anna (1930–2015)
Fidziańska-Dolot, Anna (1930–2015)
Fidziańska-Dolot, Anna (1930–2015)
Fidziańska-Dolot, Anna (1930–2015)
Fidziańska-Dolot, Anna (1930–2015)