Institutional creator:

Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular Diseases

Contributor:

Walczak, Ewa

Place of publishing:

Warsaw

Description:

Electron microscopy analysis of the heart biopsy

Abstract:

Ultrastructural analysis revealed proper sarcomere pattern, but changes in the myofibrils arrangement and their significant disorganization and/or atrophy we reevident (Fig.1-5). Features of laminopathy were observed .Cardiomyocyte nuclei of different shapes were seen, nuclear envelope was often corrugated, with numerous indentations.Many nuclei showed breaks in the nuclear membrane ,which was associated with penetration of cell organelles into the nuclei (Figs.6-17). Focally,plentiful glycogen deposits (Figs.18-20). and some vacuoles (Figs.21-23) were present Abundant fibrosis was observed in the extracellular space (Figs.24­26).

Detailed Resource Type:

Files ; Photography

Format:

pdf

Resource Identifier:

oai:rcin.org.pl:162242

Language:

pol ; eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open