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Campbell, K. H. S. ; Ritchie, W. ; Loi, P. ; McWhir, J. ; Wilmut, I.
The role of cell cycle co-ordination in the development of nuclear transfer reconstructed embryos
Komitet Biotechnologii PAN ; Instytut Chemii Bioorganicznej PAN
Exciting new opportunities in embryo cloning have been made possible by recent studies onthe interaction of the donor nucleus with the recipient cytoplasm following embryo reconstruction. The purpose of this paper is to review information regarding the co-ordination of nuclearand cytoplasmic events during embryo reconstruction, in particular the direct and indirect effectsof maturation/meiosis/mitosis promoting factor (MPF), upon the transferred nucleus. These willbe discussed in relation to DNA replication, the maintenance of correct ploidy, the occurrenceof chromosomal abnormalities and development of reconstructed embryos. Although this reviewis primarily concerned with the reconstruction of mammalian embryos, specific examples fromamphibians will also be cited.
Biotechnologia, vol.33, 2 (1996)-.
0860-7796 ; oai:rcin.org.pl:147103 ; IChB B-29
Biblioteka Instytutu Chemii Bioorganicznej PAN
Licencja Creative Commons Uznanie autorstwa-Na tych samych warunkach 4.0
Instytut Chemii Bioorganicznej Polskiej Akademii Nauk
Instytut Chemii Bioorganicznej Polskiej Akademii Nauk
13 lis 2020
13 lis 2020
58
https://rcin.org.pl./publication/182727
Nazwa wydania | Data |
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The role of cell cycle co-ordination in the development of nuclear transfer reconstructed embryos | 13 lis 2020 |
Borkowska, Bożenna
Ziółkowski, Piotr Babula- Skowrońska, Danuta Kaczmarek, Małgorzata Cieśla, Agata Sadowski, Jan
Nowak, Jacek K.