Title:

The role of cell cycle co-ordination in the development of nuclear transfer reconstructed embryos

Subtitle:

The role of cell cycle co-ordination in the development of nuclear transfer reconstructed embryos

Creator:

Campbell, K. H. S. ; Ritchie, W. ; Loi, P. ; McWhir, J. ; Wilmut, I.

Publisher:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Date issued/created:

1996

Subject and Keywords:

biotechnology

Abstract:

Exciting new opportunities in embryo cloning have been made possible by recent studies onthe interaction of the donor nucleus with the recipient cytoplasm following embryo reconstruction. The purpose of this paper is to review information regarding the co-ordination of nuclearand cytoplasmic events during embryo reconstruction, in particular the direct and indirect effectsof maturation/meiosis/mitosis promoting factor (MPF), upon the transferred nucleus. These willbe discussed in relation to DNA replication, the maintenance of correct ploidy, the occurrenceof chromosomal abnormalities and development of reconstructed embryos. Although this reviewis primarily concerned with the reconstruction of mammalian embryos, specific examples fromamphibians will also be cited.

Relation:

Biotechnologia, vol.33, 2 (1996)-.

Volume:

33

Issue:

2

Start page:

68

End page:

80

Resource type:

Text

Detailed Resource Type:

Article

Format:

application/pdf

Resource Identifier:

0860-7796 ; IChB B-29

Source:

Library of Institute of Bioorganic Chemistry PAS

Language:

eng

Language of abstract:

eng

Temporal coverage:

1988-2010

Rights:

Creative Commons Attribution BY-SA 4.0 license

Terms of use:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitizing institution:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Original in:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open