Contributor:

Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular

Place of publishing:

Warsaw

Description:

Muscle segment examination in light & electron microscopy

Abstract:

A 50-year-old patient with suspected myopathy was examined. A biopsy of quadriceps sinister was performed. Electronmicroscopy analysis revealed unchanged myofibrils structure but quite numerous fat droplets were visible (Fig. 1,2). Mitochondrial ultrastructure was preserved, and sub-membranously located cell nuclei were seen (Fig. 3,4). Normal structure of the neuromuscular junction was observed but some mitochondria were characterized by partial lack of mitochondrial cristae (Fig. 5,6,7,8,9).Defect of mitochondrial enzymes was suspected. Biochemical examination of carnitine palmitoyltransferase in the muscle biopsy was performed and the result was 2,13 nM/mgB/min (norm 6,5-18 nM/mgB/min.).

Detailed Resource Type:

Photography ; Files

Format:

pdf

Resource Identifier:

oai:rcin.org.pl:124271

Language:

pol

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open