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Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular
Muscle segment examination in light & electron microscopy
A 50-year-old patient with suspected myopathy was examined. A biopsy of quadriceps sinister was performed. Electronmicroscopy analysis revealed unchanged myofibrils structure but quite numerous fat droplets were visible (Fig. 1,2). Mitochondrial ultrastructure was preserved, and sub-membranously located cell nuclei were seen (Fig. 3,4). Normal structure of the neuromuscular junction was observed but some mitochondria were characterized by partial lack of mitochondrial cristae (Fig. 5,6,7,8,9).Defect of mitochondrial enzymes was suspected. Biochemical examination of carnitine palmitoyltransferase in the muscle biopsy was performed and the result was 2,13 nM/mgB/min (norm 6,5-18 nM/mgB/min.).
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Mossakowski Medical Research Institute PAS
Library of the Mossakowski Medical Research Institute PAS
Feb 1, 2022
May 15, 2020
42
https://rcin.org.pl./publication/111855
Edition name | Date |
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opis nr 29/10 | Feb 1, 2022 |
Fidziańska-Dolot, Anna (1930–2015)
Fidziańska-Dolot, Anna (1930–2015)
Fidziańska-Dolot, Anna (1930–2015)
Fidziańska-Dolot, Anna (1930–2015)