Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS
The article briefly presents the design and chemical synthesis of parallel stranded DNA withformation of reverse Watson-Crick base pairs. Tchurikov et al. attempted an analysis of parallelRNA-RNA duplex formation. Single stranded RNA, prepared by in vitro transcription with T7polymerase using and ^H nucleoside 5’-triphosphates, were appropriately hybridized andanalysed by polyacrylamide gel electrophoresis prior and after RNase A digestion. Results obtained allow to conclude on the formation of parallel stranded, RNA stable to RNase A. Thepresented data show the importance of intramolecular parallel association of the single strandedRNA during its folding.
Biotechnologia, vol.37, 2 (1997)-.
0860-7796 ; oai:rcin.org.pl:146113
Library of Institute of Bioorganic Chemistry PAS
Creative Commons Attribution BY-SA 4.0 license
Institute of Bioorganic Chemistry of the Polish Academy of Science
Institute of Bioorganic Chemistry of the Polish Academy of Science
Nov 18, 2020
Nov 5, 2020
98
https://rcin.org.pl./publication/181578
Borkowska, Bożenna
Ziółkowski, Piotr Babula- Skowrońska, Danuta Kaczmarek, Małgorzata Cieśla, Agata Sadowski, Jan