Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular
Muscle segment examination in light and electron microscopy
A 82-year-old patient with suspected polymyositis was examined. A biceps biopsy was performed. Electronmicroscopy analysis revealed ultrastructurally unchanged muscle fibers, characterized by preserved sarcomeres structure and normal mitochondria. Atrophied fibers, characterized by smaller diameter, accumulation of cell nuclei, disrupture/atrophy of the contractile apparatus and sometimes containing deposits of lipofuscin were also observed.Some of the fibers also showed abnormalities in the nuclei structure and / or damage to myofibrils. Infiltration of lymphocytes and plasma cells were observed in the endomysium.Microscopic image of the biopsy may suggest a past inflammatory process .
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Mossakowski Medical Research Institute PAS
Library of the Mossakowski Medical Research Institute PAS
Feb 1, 2022
Aug 27, 2020
45
https://rcin.org.pl./publication/112041
Edition name | Date |
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opis nr 24/11 | Feb 1, 2022 |
Fidziańska-Dolot, Anna (1930–2015)
Fidziańska-Dolot, Anna (1930–2015)
Fidziańska-Dolot, Anna (1930–2015)
Fidziańska-Dolot, Anna (1930–2015)