Title:

Files for neuromuscular diseases (2011) - nr 24/11

Creator:

Fidziańska-Dolot, Anna (1930–2015)

Contributor:

Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular

Place of publishing:

Warsaw

Date issued/created:

2011

Description:

Muscle segment examination in light and electron microscopy

Subject and Keywords:

Polymyositis

Abstract:

A 82-year-old patient with suspected polymyositis was examined. A biceps biopsy was performed. Electronmicroscopy analysis revealed ultrastructurally unchanged muscle fibers, characterized by preserved sarcomeres structure and normal mitochondria. Atrophied fibers, characterized by smaller diameter, accumulation of cell nuclei, disrupture/atrophy of the contractile apparatus and sometimes containing deposits of lipofuscin were also observed.Some of the fibers also showed abnormalities in the nuclei structure and / or damage to myofibrils. Infiltration of lymphocytes and plasma cells were observed in the endomysium.Microscopic image of the biopsy may suggest a past inflammatory process .

Resource type:

Text ; Image

Detailed Resource Type:

Photography ; Files

Format:

pdf

Language:

pol

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open