Contributor:

Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular

Place of publishing:

Warsaw

Abstract:

A biopsy from 7-week-old baby was taken and examined.Numerous miotube-like fibers of diameter smaller than normal and centrally located nuclei were observed. In the nuclei of these muscle fibers the phenomenon of separation the outer and inner nuclear membranes with the formation of perinuclear vacuoles was observed.Some fibers of normal diameter and sub-membranous located nuclei, characterized by the separation of the outer and inner nuclear envelopes with the formation of vacuoles adjacent to nuclei were seen. In some fibers, numerous vacuoles were present also in the cytoplasm. Myelinated and multiaxonal nerve fibers were visible in the biopsy.Conclusions: significant features of the immaturity of the muscular system with nuclear abnormali-ties were seen, what may suggest laminopathy.

Detailed Resource Type:

Photography ; Files

Format:

pdf

Resource Identifier:

oai:rcin.org.pl:136601

Language:

pol

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open