Inny tytuł:

Nonaqueous media - site of enzymatic catalysis

Wydawca:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Abstrakt:

Lipases, esterases, acylases, glycosidases, aldolases are the most used enzymes in synthetic organic chemistry. Among the biocatalysts, lipases are the most frequently used. This class of enzymes is able to catalyze the hydrolysis of carboxylic acid esters in aqueous medium on the reverse reaction in organic solvents. The use of enzymes in organic solvents is now well established and there are several advantages of conducting enzymatic reaction in water poor media such as increased solubility of hydrophobic substrates, shifting of thermodynamic equilibrium in favour of synthesis over hydrolysis and increased thermostability of the enzyme. However, the practical application of enzyme in organic solvents has been hampered by tbe low catalytic activities compared to those expressed in water. This review highlights recent research on the stabilization of enzymes using both chemical and biological means to increase the lifetime of the biocatalyst.

Czasopismo/Seria/cykl:

Biotechnologia, vol.87, 4 (2009)-.

Tom:

87

Zeszyt:

4

Strona pocz.:

168

Strona końc.:

182

Szczegółowy typ zasobu:

Article

Format:

application/pdf

Identyfikator zasobu:

0860-7796 ; oai:rcin.org.pl:71886 ; IChB B-82

Źródło:

Library of Institute of Bioorganic Chemistry PAS

Język:

pol ; pol

Język streszczenia:

eng

Zakres czasowy:

2009

Prawa:

Creative Commons Attribution BY-SA 4.0 license

Zasady wykorzystania:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitalizacja:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Lokalizacja oryginału:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Dofinansowane ze środków:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Dostęp:

Open