Subtitle:

Continuous sterilization of medium for bacitracin biosynthesis

Publisher:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Abstract:

The aim of the paper was to estimate the applicability of continuous sterilization to theimprovement of bacitracin production technology. Preliminary investigations were carried outand the effects of application of thermal continuous sterilization of substrates were estimated.The quality of sterilized substrates was assessed in fermentation tests. Bacitracin biosynthesiswas carried out on a substrate sterilized by both batch and continuous method. In laboratoryinvestigations a substrate sterilized by the continuous method enabled to increase antibioticproduction by 30% on the average as compared to the yield obtained using a batch sterilizedsubstrate. On an industrial scale, for the same inoculation material the production was evenhigher by 80%.

Relation:

Biotechnologia, vol.21, 2 (1993)-.

Volume:

21

Issue:

2

Start page:

76

End page:

82

Detailed Resource Type:

Article

Format:

application/pdf

Resource Identifier:

0860-7796 ; oai:rcin.org.pl:155728 ; IChB B-17

Source:

Library of Institute of Bioorganic Chemistry PAS

Language:

pol

Language of abstract:

eng

Temporal coverage:

1988-2010

Rights:

Creative Commons Attribution BY-SA 4.0 license

Terms of use:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitizing institution:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Original in:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open