Subtitle:

Screening methods of industrial strain mutants

Publisher:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Abstract:

The screening methods used for improvement of industrial strains are presented. Two generalcategories of methods have been distinguished: random screening and rational screening. Majortechniques employed in rational screening are based on the selection of auxotrophic mutants,revertants of non-producers, strains resistant to some factors like toxic analogues of metabolismintermediates, induction and catabolite repression or end-product inhibition, mutants with modified cell wall permeability and microorganisms tolerating some nutrients and precursors ofsecondary metabolites.

Relation:

Biotechnologia, vol.30, 3 (1995)-.

Volume:

30

Issue:

3

Start page:

104

End page:

119

Detailed Resource Type:

Article

Format:

application/pdf

Resource Identifier:

0860-7796 ; oai:rcin.org.pl:147667 ; IChB B-26

Source:

Library of Institute of Bioorganic Chemistry PAS

Language:

pol

Language of abstract:

eng

Temporal coverage:

1988-2010

Rights:

Creative Commons Attribution BY-SA 4.0 license

Terms of use:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitizing institution:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Original in:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open