Współtwórca:

Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular

Miejsce wydania:

Warsaw

Opis:

Muscle segment examination in electron microscopy

Abstrakt:

Po A 4-year-old patient was examined. A biopsy of quadriceps sinister was performed. Electronmicroscopy analysis revealed ultrastructurally changed myofibres. The vast majority of muscle fibers were characterized by centrally located nuclei, usually single or in number of two (Fig. 1,2,3,4,5,6.) In some fibers in the longitudinal section we observed a centrally arranged row of many nuclei and the evident loss of myofibril was seen (Fig. 7). The disruption of the contractile apparatus was observed, especially near the cell nuclei (Fig. 8,9,10). Abundant connective tissue was visible (Fig. 11). Ultrastructural and clinical picture suggests centronuclear myopathy associated with inappropriate BIN1 gene activity.

Szczegółowy typ zasobu:

Photography ; Files

Format:

pdf

Identyfikator zasobu:

oai:rcin.org.pl:121261

Język:

pol

Prawa:

Creative Commons Attribution BY 4.0 license

Zasady wykorzystania:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitalizacja:

Mossakowski Medical Research Institute PAS

Lokalizacja oryginału:

Library of the Mossakowski Medical Research Institute PAS

Dofinansowane ze środków:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Dostęp:

Open