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Wisowski, Grzegorz ; Olczyk, Krystyna ; Koźma, Ewa M. ; Jura-Półtorak, Agnieszka ; Olczyk, Paweł ; Kuźnik-Trocha, Kornelia
The influence of sorbitol on photooxidation-mediated crosslinking of porcine pericardial collagen
Komitet Biotechnologii PAN ; Instytut Chemii Bioorganicznej PAN
Collagen is one of the most useful biomaterials. The medical application of collagen tissues requires specific fixation procedures. Dye-mediated photooxidation is a method of the new collagen crosslink formation. In this study, the influence of sorbitol on the extent of porcine pericardial collagen crosslinking was investigated. The collagen modification was estimated on the basis of pericardial susceptibility to pepsin digestion. The hydrolysate components were characterized electrophoretically. The significant collagen crosslinking was found in all photooxidized samples, in comparison with the untreated ones. However, the most enhanced collagen modification was observed for pericardium photo- oxidized with 0,5% and 0,9% sorbitol, as compared to the samples fixed without sorbitol.
Biotechnologia, vol.71, 4 (2005)-.
0860-7796 ; oai:rcin.org.pl:89230 ; IChB B-67
Biblioteka Instytutu Chemii Bioorganicznej PAN
Licencja Creative Commons Uznanie autorstwa-Na tych samych warunkach 4.0
Instytut Chemii Bioorganicznej Polskiej Akademii Nauk
Instytut Chemii Bioorganicznej Polskiej Akademii Nauk
Oct 2, 2020
Dec 17, 2019
480
https://rcin.org.pl./publication/115930
Edition name | Date |
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Wpływ sorbitolu na sieciowanie kolagenu osierdzia wieprzowego w procesie fotooksydacji | Oct 2, 2020 |
Koźma, Ewa M. Głowacki, Andrzej Olczyk, Krystyna Wisowski, Grzegorz Olczyk, Paweł Jura-Półtorak, Agnieszka Nawrat, Zbigniew
Borkowska, Bożenna
Ziółkowski, Piotr Babula- Skowrońska, Danuta Kaczmarek, Małgorzata Cieśla, Agata Sadowski, Jan
Nowak, Jacek K.