micro RNA in pathogenesis of head and neck squamous cell carcinoma
Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS
Head and neck squamous cell carcinoma (HNSCC) is the sixth cancer in regard of both incidence and poor effect of treatment therapies, manifested in low cure rates (5-year survival rate - 50%). The molecular heterogeneity found in HNSCC is the main reason why the already published data has not been sufficient to develop reliable prognostic tests and efficient therapies. A novel group of small non-coding RNA molecules (micro RNA or miRNA) has been identified and proved to be strongly involved in cancer. However, the existing data does not specifically address micro RNA involvement in HNSCC development and progression. This report summarizes the state-of-art concerning miRNA research in head and neck cancer and provides a list of miRNAs potentially involved in HNSCC pathogenesis.
Biotechnologia, vol.90, 3 (2010)-.
oai:rcin.org.pl:71490 ; IChB B-85
Biblioteka Instytutu Chemii Bioorganicznej PAN
Creative Commons Attribution BY-SA 4.0 license
Institute of Bioorganic Chemistry of the Polish Academy of Science
Institute of Bioorganic Chemistry of the Polish Academy of Science
Oct 2, 2020
May 23, 2019
538
https://rcin.org.pl./publication/93536
Edition name | Date |
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mikro RNA w patogenezie płaskonabłonkowych raków głowy i szyi | Oct 2, 2020 |
Borkowska, Bożenna
Ziółkowski, Piotr Babula- Skowrońska, Danuta Kaczmarek, Małgorzata Cieśla, Agata Sadowski, Jan
Wielgosz, Szczęsny M. Szyfter, Krzysztof