Subtitle:

micro RNA in pathogenesis of head and neck squamous cell carcinoma

Publisher:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Abstract:

Head and neck squamous cell carcinoma (HNSCC) is the sixth cancer in regard of both incidence and poor effect of treatment therapies, manifested in low cure rates (5-year survival rate - 50%). The molecular heterogeneity found in HNSCC is the main reason why the already published data has not been sufficient to develop reliable prognostic tests and efficient therapies. A novel group of small non-coding RNA molecules (micro RNA or miRNA) has been identified and proved to be strongly involved in cancer. However, the existing data does not specifically address micro RNA involvement in HNSCC development and progression. This report summarizes the state-of-art concerning miRNA research in head and neck cancer and provides a list of miRNAs potentially involved in HNSCC pathogenesis.

Relation:

Biotechnologia, vol.90, 3 (2010)-.

Volume:

90

Issue:

3

Start page:

64

End page:

74

Detailed Resource Type:

Article

Format:

application/pdf

Resource Identifier:

oai:rcin.org.pl:71490 ; IChB B-85

Source:

Biblioteka Instytutu Chemii Bioorganicznej PAN

Language:

pol

Language of abstract:

eng

Temporal coverage:

2010

Rights:

Creative Commons Attribution BY-SA 4.0 license

Terms of use:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitizing institution:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Original in:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open