Publisher:

PZWL

Place of publishing:

Warszawa

Type of object:

Journal/Article

Abstract:

Healthy dogs divided into two groups were administered immunosuppressive agent Immuran in scope to assess organ lesions resulting from this drug. Dogs of the 1st group received low doses of Immuran, usually applied after organ transplan¬tation. In this group Immuran was administred for a 6-month period. Dogs belonging to the 2nd group were administered toxic doses of Immuran, like those used in the period of acute transplant rejection. Following symptoms and lesions were noted in both these groups: loss of body weight, leukopenia, hypalbuminemia, va¬nishing of lymphatic tissue and lesions in parenchymatous organs. One half of dogs of the 1st group survived the experimentation meanwhile all dogs of the second group died. Histological examination reveled that alterations in kidneys and livers due to Immuran administration differed from those found in allotransplants of these organs.

Relation:

Polski Przegląd Chirurgiczny

Volume:

42

Issue:

1

Start page:

24

End page:

32

Detailed Resource Type:

Article

Format:

pdf

Resource Identifier:

oai:rcin.org.pl:81290

Language:

pol

Language of abstract:

eng

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Copyright holder:

Olszewski, Waldemar

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open