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Oligonucleotides as potential therapeutic tools against hepatitis C virus
Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS
Hepatitis C virus belongs to the group of particularly dangerous and most extensively studied RNA viruses. Since no vaccine for HCV is known and post-exposure treatment of infected patients has not been yet optimal, novel therapeutic strategies are being developed very intensively. Oligonucleotide-based molecular tools such as antisense oligonucleotides, ribozymes, DNAzymes, aptamers and interfering RNAs are proving as effective modulators of gene expression and potential therapeutics. Several examples of oligonucleotide-based molecular tools directed towards HCV viral RNA are discussed in this review.
Biotechnologia, vol.88, 1 (2010)-.
0860-7796 ; oai:rcin.org.pl:71733 ; IChB B-83
Library of Institute of Bioorganic Chemistry PAS
Creative Commons Attribution BY-SA 4.0 license
Institute of Bioorganic Chemistry of the Polish Academy of Science
Institute of Bioorganic Chemistry of the Polish Academy of Science
Oct 2, 2020
May 28, 2019
203
https://rcin.org.pl./publication/94048
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