Inny tytuł:

The application of monoclonal antibodies to medical treatment

Wydawca:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Abstrakt:

In this review contemporary trends in the application of monoclonal antibodies are presented.There is discussed antibody reengineering for humanization of mouse monoclonal antibodies toavoid anti-globulin reaction of patient. Recent modifications of antibody fragments are also outlined. The most common antigenic structures exposed to antibody attack are characterized. Someaspects of human monoclonal antibody production are briefly described. Three most promisingtherapeutic antibodies — bispecific antibodies, immunotoxins, and radiolabeled immunoconjugates — are presented.

Czasopismo/Seria/cykl:

Biotechnologia, vol.21, 2 (1993)-.

Tom:

21

Zeszyt:

2

Strona pocz.:

105

Strona końc.:

120

Szczegółowy typ zasobu:

Article

Format:

application/pdf

Identyfikator zasobu:

0860-7796 ; oai:rcin.org.pl:155731 ; IChB B-17

Źródło:

Library of Institute of Bioorganic Chemistry PAS

Język:

pol

Język streszczenia:

eng

Zakres czasowy:

1988-2010

Prawa:

Creative Commons Attribution BY-SA 4.0 license

Zasady wykorzystania:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitalizacja:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Lokalizacja oryginału:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Dofinansowane ze środków:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Dostęp:

Open