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The application of monoclonal antibodies to medical treatment
Komitet Biotechnologii PAN ; Instytut Chemii Bioorganicznej PAN
In this review contemporary trends in the application of monoclonal antibodies are presented.There is discussed antibody reengineering for humanization of mouse monoclonal antibodies toavoid anti-globulin reaction of patient. Recent modifications of antibody fragments are also outlined. The most common antigenic structures exposed to antibody attack are characterized. Someaspects of human monoclonal antibody production are briefly described. Three most promisingtherapeutic antibodies — bispecific antibodies, immunotoxins, and radiolabeled immunoconjugates — are presented.
Biotechnologia, vol.21, 2 (1993)-.
0860-7796 ; oai:rcin.org.pl:155731 ; IChB B-17
Biblioteka Instytutu Chemii Bioorganicznej PAN
Licencja Creative Commons Uznanie autorstwa-Na tych samych warunkach 4.0
Instytut Chemii Bioorganicznej Polskiej Akademii Nauk
Instytut Chemii Bioorganicznej Polskiej Akademii Nauk
Jan 21, 2021
Jan 21, 2021
563
https://rcin.org.pl./publication/189985
Edition name | Date |
---|---|
Wykorzystanie przeciwciał monoklonalnych do celów terapeutycznych | Jan 21, 2021 |
Borkowska, Bożenna
Ziółkowski, Piotr Babula- Skowrońska, Danuta Kaczmarek, Małgorzata Cieśla, Agata Sadowski, Jan
Nowak, Jacek K.