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Chemical Combinatorial Libraries — Their Synthesis and Applications
Komitet Biotechnologii PAN ; Instytut Chemii Bioorganicznej PAN
The paper reviews the new methodologies of synthesis and screening of combinatorial libraries of chemical compounds (CCL). The original classification of chemical combinatorial librariesis presented. The combinatorial libraries of chemical compounds are the collections of low (peptides, their analogues, oligonucleotides etc.) or high molecular compounds (fragment antibodies,chemically modified phages etc.). They can be obtained via chemical or chemical/biological routesand screened with labelled acceptor (substrate) molecules in order to reveal those of interactinglibrary entities which best meet the selection criteria (conditions of selection). The potentialapplications of CCLs in basic research and technology are indicated.
Biotechnologia, vol.32, 1 (1996)-.
0860-7796 ; oai:rcin.org.pl:147322 ; IChB B-28
Biblioteka Instytutu Chemii Bioorganicznej PAN
Licencja Creative Commons Uznanie autorstwa-Na tych samych warunkach 4.0
Instytut Chemii Bioorganicznej Polskiej Akademii Nauk
Instytut Chemii Bioorganicznej Polskiej Akademii Nauk
Nov 16, 2020
Nov 16, 2020
590
https://rcin.org.pl./publication/182967
Edition name | Date |
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Chemiczne biblioteki kombinatoryczne — ich synteza i zastosowania | Nov 16, 2020 |
Tyczewska, Agata Bąkowska- Żywicka, Kamila
Pieczyński, Marcin Bielewicz, Dawid Dolata, Jakub Szweykowska-Kulińska, Zofia