Kowalczuk, Maria ; Mackiewicz, Dorota ; Mackiewicz, Paweł ; Polak, Natalia ; Cebrat, Stanisław
Influence of replication on organization and evolution of bacterial genomes
Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS
In bacterial chromosomes, strong bias in nucleotide composition has been observed between differently replicated DNA strands (leading and lagging ones), and also in many species between the regions proximal and distal to the origin of replication (on). This bias is also reflected in composition and distribution of genes along the chromosome. Several phenomena connected with the replication of the chromosome are responsible for such polarization, especially mutational pressure, repair mechanisms and recombinations, and also selection pressure. All these phenomena are not indifferent for gene evolution and their rearrangements which are strictly connected with the organization of bacterial chromosome.
Biotechnologia, vol.70, 3 (2005)-.
0860-7796 ; oai:rcin.org.pl:91827 ; IChB B-66
Library of Institute of Bioorganic Chemistry PAS
Creative Commons Attribution BY-SA 4.0 license
Institute of Bioorganic Chemistry of the Polish Academy of Science
Institute of Bioorganic Chemistry of the Polish Academy of Science
Oct 2, 2020
Dec 19, 2019
367
https://rcin.org.pl./publication/118312
Edition name | Date |
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Wpływ replikacji na organizację i ewolucję genomów bakterii | Oct 2, 2020 |
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