Contributor:

Mossakowski Medical Research Center Polish Academy of Sciences. Department of Neuromuscular

Place of publishing:

Warsaw

Description:

Muscle segment examination in light and electron microscopy

Abstract:

A patient with suspected myopathy was examined. A biopsy was taken.Electronmicroscopy analysis revealed, in addition to the muscle fibers of the correct diameter andthe preserved myofibril structure, numerous fibers of very small diameter characterized by thepresence of peripherally located ring-binden structures.In some fibers atrophy of the contractile apparatus and accumulation of abnormal mitochondriawere seen.Mitochondria with blurred structure of mitochondrial cristae or partial lack of them were observed.In some mitochondria cristae formed abnormal structures. Also giant mitochondria, many timeslarger than typical were visible.The location of nuclei was normal, sub-membranous, but in some nuclei rupture of the nuclearmembrane and nuclear damage was observed .

Detailed Resource Type:

Photography ; Files

Format:

pdf

Resource Identifier:

oai:rcin.org.pl:141434

Language:

pol

Rights:

Creative Commons Attribution BY 4.0 license

Terms of use:

Copyright-protected material. [CC BY 4.0] May be used within the scope specified in Creative Commons Attribution BY 4.0 license, full text available at: ; -

Digitizing institution:

Mossakowski Medical Research Institute PAS

Original in:

Library of the Mossakowski Medical Research Institute PAS

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open