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RCIN and OZwRCIN projects

Object

Title: Immunoreactive and Estrogen-binding estrogen receptors, and progestin receptor levels in uterine leiomyomata and their parental myometrium

Type of object:

Journal/Article

Abstract:

Estrogen receptor (ER) and progestin receptor (PR) levels in the myometria and uterine leiomyomata of forty-four women were studied. A radiolligand method and an immuno-enzymatic method were used for ER measurement, and only a radio-ligand method was used for PR measurement. The leiomyomata contained significantly more PR and estrogen-binding ER than their parental myometria but not the immunoreactive ER per mg of DNA. Nuclear extracts from the myometria contained a high amount of the estrogen-nonbinding immunoreactive ER; in the leiomyomata, the bulk of this particular ER fraction was extracted with cytosol. Dissimilar distribution patterns of immunoreactive, estrogen-nonbinding ER in leiomyomata and normal myo-metria suggest that an impaired metabolism of ER may contribute to myoma growth

Relation:

European Journal Gynaecology Oncology

Volume:

11

Issue:

4

Start page:

275

End page:

281

Detailed Resource Type:

Article

Format:

application/pdf

Resource Identifier:

oai:rcin.org.pl:76911

Language:

eng

Language of abstract:

eng

Rights:

Licencja Creative Commons Uznanie autorstwa 4.0

Terms of use:

Zasób chroniony prawem autorskim. [CC BY 4.0 Międzynarodowe] Korzystanie dozwolone zgodnie z licencją Creative Commons Uznanie autorstwa 4.0, której pełne postanowienia dostępne są pod adresem: ; -

Digitizing institution:

Instytut Medycyny Doświadczalnej i Klinicznej im. M. Mossakowskiego Polskiej Akademii Nauk

Original in:

Biblioteka Instytutu Medycyny Doświadczalnej i Klinicznej im. M. Mossakowskiego PAN

Projects co-financed by:

Program Operacyjny Polska Cyfrowa, lata 2014-2020, Działanie 2.3 : Cyfrowa dostępność i użyteczność sektora publicznego; środki z Europejskiego Funduszu Rozwoju Regionalnego oraz współfinansowania krajowego z budżetu państwa

Access:

Open

Object collections:

Last modified:

Mar 24, 2022

In our library since:

Aug 1, 2019

Number of object content downloads / hits:

78

All available object's versions:

https://rcin.org.pl./publication/100893

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