Subtitle:

Recycling of eucaryotic ribosomes

Publisher:

Committee on Biotechnology PAS ; Institute of Bioorganic Chemistry PAS

Type of object:

Journal/Article

Abstract:

Until recently protein biosynthesis has been viewed as a process involving only three steps: initiation of translation, elongation of the nascent polypeptide chain and release of the completed unfolded polypeptide. In recent years fourth step in translation has been distinguished - it is the recycling of the ribosome. In this process posttermination complexes termed post-TC consisting of ribosomes with deacylated tRNA(s) and mRNA are dissociated with the help of ribosome recycling factor (RRF), elongation factor G (EF-G) and initiation factor 3 (1F3) in Procaryotes. The mechanism of this final step in Eucaryotes was unknown for a long time, but the work of Pisarev et al. sheds a light on splitting 80S ribosomes and preparing them for the next cycle of translation.

Relation:

Biotechnologia, vol.84, 1 (2009)-.

Volume:

84

Issue:

1

Start page:

81

End page:

85

Detailed Resource Type:

Article

Format:

application/pdf

Resource Identifier:

0860-7796 ; oai:rcin.org.pl:73113 ; IChB B-79

Source:

Library of Institute of Bioorganic Chemistry PAS

Language:

pol

Language of abstract:

eng

Temporal coverage:

2009

Rights:

Creative Commons Attribution BY-SA 4.0 license

Terms of use:

Copyright-protected material. [CC BY-SA 4.0] May be used within the scope specified in Creative Commons Attribution BY-SA 4.0 license, full text available at:

Digitizing institution:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Original in:

Institute of Bioorganic Chemistry of the Polish Academy of Science

Projects co-financed by:

Operational Program Digital Poland, 2014-2020, Measure 2.3: Digital accessibility and usefulness of public sector information; funds from the European Regional Development Fund and national co-financing from the state budget.

Access:

Open