• Search in all Repository
  • Literature and maps
  • Archeology
  • Mills database
  • Natural sciences

Search in Repository

How to search...

Advanced search

Search in Literature and maps

How to search...

Advanced search

Search in Archeology

How to search...

Advanced search

Search in Mills database

How to search...

Advanced search

Search in Natural sciences

How to search...

Advanced search

RCIN and OZwRCIN projects

Object

Title: Rybozymy w medycynie

Creator:

Antoszczyk, Sławomir ; Nawrot, Barbara

Date issued/created:

2003

Resource type:

Tekst

Subtitle:

Ribozymes in medicine

Publisher:

Komitet Biotechnologii PAN ; Instytut Chemii Bioorganicznej PAN

Abstract:

Catalytic nucleic acids, ribozymes and deoxyribozymes can act as efficientribonucleases and degrade target RNA molecules by complementary Watson-Crick base pairing and catalytic cleavage of their phosphodiesterinternucleotide bonds. This ability makes ribozymes and deoxyribozymes potent molecular tools for therapeutic applications. Recent achievements inribozymes design and technology enable the preparation of ribozymes whichcan be efficiently expressed in cellular systems, co-localize with the targetmRNA and exhibit high intracellular activity. Several examples of preclinical andclinical trials of ribozymes directed toward viral genes (HBV, HCV, HIV-1) andoncogenes are discussed in this review.

Relation:

Biotechnologia, vol.61, 2 (2003)-.

Volume:

61

Issue:

2

Start page:

140

End page:

152

Detailed Resource Type:

Artykuł

Format:

application/pdf

Resource Identifier:

0860-7796 ; oai:rcin.org.pl:135641 ; IChB B-57

Source:

Biblioteka Instytutu Chemii Bioorganicznej PAN

Language:

pol

Language of abstract:

eng

Temporal coverage:

1988-2010

Rights:

Licencja Creative Commons Uznanie autorstwa-Na tych samych warunkach 4.0

Terms of use:

-

Digitizing institution:

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Original in:

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Projects co-financed by:

Program Operacyjny Polska Cyfrowa, lata 2014-2020, Działanie 2.3 : Cyfrowa dostępność i użyteczność sektora publicznego; środki z Europejskiego Funduszu Rozwoju Regionalnego oraz współfinansowania krajowego z budżetu państwa

Access:

Otwarty

Object collections:

Last modified:

Oct 2, 2020

In our library since:

Aug 19, 2020

Number of object content downloads / hits:

1361

All available object's versions:

https://rcin.org.pl./publication/170581

Show description in RDF format:

RDF

Show description in RDFa format:

RDFa

Show description in OAI-PMH format:

OAI-PMH

Edition name Date
Rybozymy w medycynie Oct 2, 2020
×

Citation

Citation style:

This page uses 'cookies'. More information