Production of paclitaxel and other taxanes in in vitro cultures
Komitet Biotechnologii PAN ; Instytut Chemii Bioorganicznej PAN
KULTURY IN VITRO I BIOTECHNOLOGIA ROŚLIN
Paclitaxel is an effective important anticancer drug for advanced breast,ovarian and other cancers. It was first isolated from the bark of the Pacific yew(Taxus brevifolia). Paclitaxel belongs to a group of secondary metabolites collectively indicated with the name taxanes. Paclitaxel is found in most yews, but thecontent is very (0-0,05%) variable. Because of the scarcity of the slow growingtrees and the relative low content of paclitaxel, alternative sources are neededto meet the increasing demand. The literature concerning the tissue culture ofTaxus sp. as an alternative source for taxanes production in reviewed.
Biotechnologia, vol.62, 3 (2003)-.
0860-7796 ; oai:rcin.org.pl:133141 ; IChB B-58
Biblioteka Instytutu Chemii Bioorganicznej PAN
Licencja Creative Commons Uznanie autorstwa-Na tych samych warunkach 4.0
Instytut Chemii Bioorganicznej Polskiej Akademii Nauk
Instytut Chemii Bioorganicznej Polskiej Akademii Nauk
Oct 2, 2020
Jul 21, 2020
505
https://rcin.org.pl./publication/167806
Edition name | Date |
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Wytwarzanie paklitakselu i innych taksanów w kulturach in vitro | Oct 2, 2020 |
Borkowska, Bożenna
Ziółkowski, Piotr Babula- Skowrońska, Danuta Kaczmarek, Małgorzata Cieśla, Agata Sadowski, Jan
Nowak, Jacek K.