Recycling of eucaryotic ribosomes
Komitet Biotechnologii PAN ; Instytut Chemii Bioorganicznej PAN
Until recently protein biosynthesis has been viewed as a process involving only three steps: initiation of translation, elongation of the nascent polypeptide chain and release of the completed unfolded polypeptide. In recent years fourth step in translation has been distinguished - it is the recycling of the ribosome. In this process posttermination complexes termed post-TC consisting of ribosomes with deacylated tRNA(s) and mRNA are dissociated with the help of ribosome recycling factor (RRF), elongation factor G (EF-G) and initiation factor 3 (1F3) in Procaryotes. The mechanism of this final step in Eucaryotes was unknown for a long time, but the work of Pisarev et al. sheds a light on splitting 80S ribosomes and preparing them for the next cycle of translation.
2009 ; Biotechnologia, vol.84, 1 (2009)-.
0860-7796 ; oai:rcin.org.pl:73113 ; IChB B-79
Biblioteka Instytutu Chemii Bioorganicznej PAN
Licencja Creative Commons Uznanie autorstwa-Na tych samych warunkach 4.0
Instytut Chemii Bioorganiczneji Polskiej Akademii Nauk
Instytut Chemii Bioorganiczneji Polskiej Akademii Nauk
2 paź 2020
15 cze 2019
89
https://rcin.org.pl./publication/95764
Nazwa wydania | Data |
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Recycling of eucaryotic ribosomes | 2 paź 2020 |
Tyczewska, Agata Bąkowska-Żywicka, Kamilla
Bąkowska-Żywicka, Kamilla Tyczewska, Agata
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